武汉大学汪晖教授：烟酒致胎儿发育迟缓之谜初揭
<p class="MsoNormal" style="MARGIN: 0cm 0cm 0pt; TEXT-INDENT: 28.1pt; TEXT-ALIGN: center; mso-char-indent-count: 2.0" align="center"><b style="mso-bidi-font-weight: normal"><span style="FONT-SIZE: 14pt; COLOR: #993300; FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-hansi-font-family: "Times New Roman"">武汉大学汪晖教授：烟酒致胎儿发育迟缓之谜初揭</span></b><b style="mso-bidi-font-weight: normal"><span lang="EN-US" style="FONT-SIZE: 14pt; COLOR: #993300"><p /></span></b></p><p class="MsoNormal" style="MARGIN: 0cm 0cm 0pt; TEXT-INDENT: 21pt; mso-char-indent-count: 2.0"><span lang="EN-US"><font size="3"><font face="Times New Roman"><span style="mso-spacerun: yes"> </span><span style="mso-spacerun: yes"> </span><p /></font></font></span></p><p class="MsoNormal" style="MARGIN: 0cm 0cm 0pt; TEXT-INDENT: 21pt; mso-char-indent-count: 2.0"><font size="3"><span style="FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-hansi-font-family: "Times New Roman"">尼古丁等通过母体进入胎儿体内，胎儿重要内分泌器官肾上腺可能因代谢这些外源物，损伤其内分泌功能，从而导致宫内发育迟缓。</span><font face="Times New Roman"> <span lang="EN-US"><p /></span></font></font></p><p class="MsoNormal" style="MARGIN: 0cm 0cm 0pt; TEXT-INDENT: 21pt; mso-char-indent-count: 2.0"><font size="3"><span style="FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-hansi-font-family: "Times New Roman"">武汉大学医学院基础医学院副院长汪晖教授这一最新发现，初步揭开了烟酒致胎儿发育迟缓之谜。此前，烟酒等致使胎儿发育不良，已被临床和流行病学所证实，但其机理一直不清。</span><font face="Times New Roman"> <span lang="EN-US"><p /></span></font></font></p><p class="MsoNormal" style="MARGIN: 0cm 0cm 0pt; TEXT-INDENT: 21pt; mso-char-indent-count: 2.0"><font size="3"><span style="FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-hansi-font-family: "Times New Roman"">其课题组最近发现，孕期接触尼古丁、乙醇、咖啡因等可引起胎儿宫内发育迟缓。汪晖昨日介绍，胎儿肾上腺所具有的外源物代谢功能会干扰自身的正常发育，从而损伤其内分泌功能，影响胎儿的甾体激素合成，导致宫内发育迟缓。其研究结果已在国内外专业期刊上发表。不过，汪晖坦承，有关其机制的更本质揭示正在研究中。</span><font face="Times New Roman"> <span lang="EN-US"><p /></span></font></font></p><p class="MsoNormal" style="MARGIN: 0cm 0cm 0pt; TEXT-INDENT: 21pt; mso-char-indent-count: 2.0"><font size="3"><span style="FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-hansi-font-family: "Times New Roman"">宫内发育迟缓是指孕周大于</span><span lang="EN-US"><font face="Times New Roman">37</font></span><span style="FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-hansi-font-family: "Times New Roman"">周而胎儿出生体重小于</span><chmetcnv w:st="on" tcsc="0" numbertype="1" negative="False" hasspace="False" sourcevalue="2500" unitname="克"><span lang="EN-US"><font face="Times New Roman">2500</font></span><span style="FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-hansi-font-family: "Times New Roman"">克</span></chmetcnv><span style="FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-hansi-font-family: "Times New Roman"">。在我国，其发病率约为</span><span lang="EN-US"><font face="Times New Roman">6.39%%</font></span><span style="FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-hansi-font-family: "Times New Roman"">。其危害可造成胎儿窘迫、新生儿窒息和围产儿死亡，对胎儿的危害将延续到成年，可使成年后的心血管系统、神经系统和代谢性疾病发病率升高。</span><font face="Times New Roman"> <span lang="EN-US"><p /></span></font></font></p><p class="MsoNormal" style="MARGIN: 0cm 0cm 0pt; TEXT-INDENT: 21pt; mso-char-indent-count: 2.0"><font size="3"><span style="FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-hansi-font-family: "Times New Roman"">肾上腺被公认是人体重要的内分泌器官。上世纪</span><span lang="EN-US"><font face="Times New Roman">90</font></span><span style="FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-hansi-font-family: "Times New Roman"">年代后期，汪晖与其导师彭仁琇教授却在一研究中证实，胎儿肾上腺不仅是一内分泌器官，同时也是一个重要的外源物代谢器官。</span><font face="Times New Roman"> <span lang="EN-US"><p /></span></font></font></p><p class="MsoNormal" style="MARGIN: 0cm 0cm 0pt; TEXT-INDENT: 21pt; mso-char-indent-count: 2.0"><font size="3"><span style="FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-hansi-font-family: "Times New Roman"">此后，汪晖一直没有放弃对这一问题的追踪。胎儿肾上腺及其代谢功能与胎儿宫内发育迟缓有什么关联？这一问题近期受到汪晖及其课题组的极大关注，在此基础上他们进行了相关工作并初步有了上述结果。</span><font face="Times New Roman"> <span lang="EN-US"><p /></span></font></font></p><p class="MsoNormal" style="MARGIN: 0cm 0cm 0pt; TEXT-INDENT: 21pt; mso-char-indent-count: 2.0"><font size="3"><span style="FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-hansi-font-family: "Times New Roman"">据介绍，临床上，宫内发育迟缓的诱因多为孕期母体暴露于外源物所致。已证实能引起宫内迟缓发生的外源物有毒物如烟、空气污染物、毒品、有机磷杀虫剂等，药物如地塞米松、咖啡因、阿斯匹林、抗癫痫药、来普汀、内皮素、抗凝剂、抗惊厥药等，饮料如酒、咖啡、茶、可乐等。</span><font face="Times New Roman"> <span lang="EN-US"><p /></span></font></font></p><p class="MsoNormal" style="MARGIN: 0cm 0cm 0pt; TEXT-INDENT: 21pt; mso-char-indent-count: 2.0"><font size="3"><span style="FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-hansi-font-family: "Times New Roman"">此外，他们还意外发现，孕妇吸烟后再服用吲哚</span><span lang="EN-US"><font face="Times New Roman">3-</font></span><span style="FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-hansi-font-family: "Times New Roman"">原醇（十字花科蔬菜中的主要单体成分），可加重吸烟所致的胚胎毒性。因此，孕妇主动或者被动吸烟的同时，不宜食用西兰花等十字花科蔬菜。该研究论文已在国外某杂志上发表。此前，西兰花被证实不会影响胎儿的正常发育。（瞿凌云）</span></font></p> 孕妇不为自己着想,也应该为胎儿着想,健康是福.
页:
[1]